1ndn: Difference between revisions

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[[Image:1ndn.jpg|left|200px]]<br /><applet load="1ndn" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1ndn.jpg|left|200px]]<br /><applet load="1ndn" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1ndn, resolution 3.000Å" />

'''MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4'''<br />

==Overview==

The molecular structure of a nicked dodecamer DNA double helix, made of a, ternary system containing d(CGCGAAAACGCG) + d(CGCGTT) + d(TTCGCG), oligonucleotides, has been determined by x-ray diffraction analysis at 3 A, resolution. The molecule adopts a B-DNA conformation, not unlike those, found in intact dodecamer DNA molecules crystallized in a somewhat, different crystal lattice, despite a gap due to the absence of a phosphate, group in the molecule. The helix has a distinct narrow minor groove near, the center of the molecule at the AAAA region. This suggests that the, internal stabilizing forces due to base stacking and hydrogen-bonding, interactions are sufficient to overcome the loss of connectivity, associated with the disruption of the covalent backbone of DNA.

The molecular structure of a nicked dodecamer DNA double helix, made of a ternary system containing d(CGCGAAAACGCG) + d(CGCGTT) + d(TTCGCG) oligonucleotides, has been determined by x-ray diffraction analysis at 3 A resolution. The molecule adopts a B-DNA conformation, not unlike those found in intact dodecamer DNA molecules crystallized in a somewhat different crystal lattice, despite a gap due to the absence of a phosphate group in the molecule. The helix has a distinct narrow minor groove near the center of the molecule at the AAAA region. This suggests that the internal stabilizing forces due to base stacking and hydrogen-bonding interactions are sufficient to overcome the loss of connectivity associated with the disruption of the covalent backbone of DNA.

==About this Structure==

1NDN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1NDN OCA].

1NDN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDN OCA].

==Reference==

Line 13:

[[Category: Protein complex]]

[[Category: Aymani, J.]]

[[Category: Boom, J.H.Van.]]

[[Category: Boom, J H.Van.]]

[[Category: Coll, M.]]

[[Category: Marel, G.A.Van.Der.]]

[[Category: Marel, G A.Van Der.]]

[[Category: Rich, A.]]

[[Category: Wang, A.H.J.]]

[[Category: Wang, A H.J.]]

[[Category: b-dna]]

[[Category: double helix]]

[[Category: nicked]]

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@@ Line 1: / Line 1: @@
-[[Image:1ndn.jpg|left|200px]]<br /><applet load="1ndn" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1ndn.jpg|left|200px]]<br /><applet load="1ndn" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1ndn, resolution 3.000&Aring;" />
 '''MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4'''<br />
 ==Overview==
-The molecular structure of a nicked dodecamer DNA double helix, made of a, ternary system containing d(CGCGAAAACGCG) + d(CGCGTT) + d(TTCGCG), oligonucleotides, has been determined by x-ray diffraction analysis at 3 A, resolution. The molecule adopts a B-DNA conformation, not unlike those, found in intact dodecamer DNA molecules crystallized in a somewhat, different crystal lattice, despite a gap due to the absence of a phosphate, group in the molecule. The helix has a distinct narrow minor groove near, the center of the molecule at the AAAA region. This suggests that the, internal stabilizing forces due to base stacking and hydrogen-bonding, interactions are sufficient to overcome the loss of connectivity, associated with the disruption of the covalent backbone of DNA.
+The molecular structure of a nicked dodecamer DNA double helix, made of a ternary system containing d(CGCGAAAACGCG) + d(CGCGTT) + d(TTCGCG) oligonucleotides, has been determined by x-ray diffraction analysis at 3 A resolution. The molecule adopts a B-DNA conformation, not unlike those found in intact dodecamer DNA molecules crystallized in a somewhat different crystal lattice, despite a gap due to the absence of a phosphate group in the molecule. The helix has a distinct narrow minor groove near the center of the molecule at the AAAA region. This suggests that the internal stabilizing forces due to base stacking and hydrogen-bonding interactions are sufficient to overcome the loss of connectivity associated with the disruption of the covalent backbone of DNA.
 ==About this Structure==
-NDN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NDN OCA].
+NDN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDN OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Protein complex]]
 [[Category: Aymani, J.]]
-[[Category: Boom, J.H.Van.]]
+[[Category: Boom, J H.Van.]]
 [[Category: Coll, M.]]
-[[Category: Marel, G.A.Van.Der.]]
+[[Category: Marel, G A.Van Der.]]
 [[Category: Rich, A.]]
-[[Category: Wang, A.H.J.]]
+[[Category: Wang, A H.J.]]
 [[Category: b-dna]]
 [[Category: double helix]]
 [[Category: nicked]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 22:58:16 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:05:03 2008''