3gw5: Difference between revisions
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[[Image:3gw5.png|left|200px]] | |||
[[Image:3gw5. | |||
{{STRUCTURE_3gw5| PDB=3gw5 | SCENE= }} | {{STRUCTURE_3gw5| PDB=3gw5 | SCENE= }} | ||
===Crystal structure of human renin complexed with a novel inhibitor=== | ===Crystal structure of human renin complexed with a novel inhibitor=== | ||
{{ABSTRACT_PUBMED_19457666}} | {{ABSTRACT_PUBMED_19457666}} | ||
== | ==About this Structure== | ||
[[3gw5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GW5 OCA]. | |||
== | ==See Also== | ||
*[[Renin|Renin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019457666</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
[[Category: McKeever, B M.]] | [[Category: McKeever, B M.]] | ||
[[Category: Wu, Z.]] | [[Category: Wu, Z.]] | ||
[[Category: Aspartate protease]] | [[Category: Aspartate protease]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydrolase | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Hypertension]] | [[Category: Hypertension]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Renin]] | [[Category: Renin]] | ||
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[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 16:19, 20 October 2012
Crystal structure of human renin complexed with a novel inhibitor
Template:ABSTRACT PUBMED 19457666
About this Structure
3gw5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tice CM, Xu Z, Yuan J, Simpson RD, Cacatian ST, Flaherty PT, Zhao W, Guo J, Ishchenko A, Singh SB, Wu Z, Scott BB, Bukhtiyarov Y, Berbaum J, Mason J, Panemangalore R, Cappiello MG, Muller D, Harrison RK, McGeehan GM, Dillard LW, Baldwin JJ, Claremon DA. Design and optimization of renin inhibitors: Orally bioavailable alkyl amines. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3541-5. Epub 2009 May 5. PMID:19457666 doi:10.1016/j.bmcl.2009.04.140
