3h0b: Difference between revisions
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[[Image:3h0b.png|left|200px]] | |||
[[Image:3h0b. | |||
{{STRUCTURE_3h0b| PDB=3h0b | SCENE= }} | {{STRUCTURE_3h0b| PDB=3h0b | SCENE= }} | ||
===Discovery of aminoheterocycles as a novel beta-secretase inhibitor class=== | ===Discovery of aminoheterocycles as a novel beta-secretase inhibitor class=== | ||
{{ABSTRACT_PUBMED_19409780}} | {{ABSTRACT_PUBMED_19409780}} | ||
==About this Structure== | ==About this Structure== | ||
[[3h0b]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H0B OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019409780</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Allison, T J.]] | [[Category: Allison, T J.]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 08:50, 26 July 2012
Discovery of aminoheterocycles as a novel beta-secretase inhibitor class
Template:ABSTRACT PUBMED 19409780
About this Structure
3h0b is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Stachel SJ, Coburn CA, Rush D, Jones KL, Zhu H, Rajapakse H, Graham SL, Simon A, Katharine Holloway M, Allison TJ, Munshi SK, Espeseth AS, Zuck P, Colussi D, Wolfe A, Pietrak BL, Lai MT, Vacca JP. Discovery of aminoheterocycles as a novel beta-secretase inhibitor class: pH dependence on binding activity part 1. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2977-80. Epub 2009 Apr 18. PMID:19409780 doi:10.1016/j.bmcl.2009.04.033
