3dcs: Difference between revisions

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{{Seed}}
[[Image:3dcs.png|left|200px]]
[[Image:3dcs.png|left|200px]]


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{{STRUCTURE_3dcs|  PDB=3dcs  |  SCENE=  }}  
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===Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties===
===Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties===


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{{ABSTRACT_PUBMED_19170619}}
{{ABSTRACT_PUBMED_19170619}}


==Disease==
==About this Structure==
Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611492 611492]]
[[3dcs]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DCS OCA].


==About this Structure==
==See Also==
3DCS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DCS OCA].
*[[Carbonic anhydrase|Carbonic anhydrase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19170619</ref><references group="xtra"/>
<ref group="xtra">PMID:019170619</ref><references group="xtra"/>
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 35: Line 23:
[[Category: Mckenna, R.]]
[[Category: Mckenna, R.]]
[[Category: Sippel, K H.]]
[[Category: Sippel, K H.]]
[[Category: Acetylation]]
[[Category: Caix mimic inhibitor]]
[[Category: Caix mimic inhibitor]]
[[Category: Carbonic anhydrase ii complex]]
[[Category: Carbonic anhydrase ii complex]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Lyase]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Polymorphism]]
[[Category: Zinc]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  8 12:54:04 2009''

Revision as of 19:45, 25 July 2012

File:3dcs.png

Template:STRUCTURE 3dcs

Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties

Template:ABSTRACT PUBMED 19170619

About this Structure

3dcs is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Genis C, Sippel KH, Case N, Cao W, Avvaru BS, Tartaglia LJ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rosser CJ, McKenna R. Design of a Carbonic Anhydrase IX Active-Site Mimic To Screen Inhibitors for Possible Anticancer Properties (dagger) (double dagger). Biochemistry. 2009 Jan 26. PMID:19170619 doi:10.1021/bi802035f

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