3h2x: Difference between revisions
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[[Image:3h2x.png|left|200px]] | [[Image:3h2x.png|left|200px]] | ||
{{STRUCTURE_3h2x| PDB=3h2x | SCENE= }} | {{STRUCTURE_3h2x| PDB=3h2x | SCENE= }} | ||
===Crystal Structure of The Human Lymphoid Tyrosine Phosphatase Catalytic Domain=== | ===Crystal Structure of The Human Lymphoid Tyrosine Phosphatase Catalytic Domain=== | ||
{{ABSTRACT_PUBMED_19371084}} | {{ABSTRACT_PUBMED_19371084}} | ||
==About this Structure== | ==About this Structure== | ||
[[3h2x]] is a 1 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H2X OCA]. | |||
==See Also== | |||
*[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]] | |||
*[[Tyrosine phosphatase|Tyrosine phosphatase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019371084</ref><ref group="xtra">PMID:021341673</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
[[Category: Sen, U.]] | [[Category: Sen, U.]] | ||
[[Category: Tsai, S J.]] | [[Category: Tsai, S J.]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Protein phosphatase]] | [[Category: Protein phosphatase]] | ||
[[Category: Sh2-like fold]] | [[Category: Sh2-like fold]] | ||
[[Category: Systemic lupus erythematosus]] | [[Category: Systemic lupus erythematosus]] | ||
Revision as of 22:10, 26 July 2012
Crystal Structure of The Human Lymphoid Tyrosine Phosphatase Catalytic Domain
Template:ABSTRACT PUBMED 19371084
About this Structure
3h2x is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tsai SJ, Sen U, Zhao L, Greenleaf WB, Dasgupta J, Fiorillo E, Orru V, Bottini N, Chen XS. Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation . Biochemistry. 2009 Jun 9;48(22):4838-45. PMID:19371084 doi:10.1021/bi900166y
- Stanford SM, Krishnamurthy D, Falk MD, Messina R, Debnath B, Li S, Liu T, Kazemi R, Dahl R, He Y, Yu X, Chan AC, Zhang ZY, Barrios AM, Woods VL Jr, Neamati N, Bottini N. Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells. J Med Chem. 2011 Mar 24;54(6):1640-54. Epub 2011 Feb 22. PMID:21341673 doi:10.1021/jm101202j