Sandbox Z-DNA: Difference between revisions
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== Structure == | == Structure == | ||
Z-DNA can form ''invitro'' from B-DNA by raising negative super helical stress or under physiological salt conditions when deoxycytosine is 5-methylated. The formation of Z-DNA which requires energy is an active process ''invivo''. A mechanism for initiation of Z-DNA involves formation of negative supercoils behind a moving RNA polymerase when it moves through DNA double helix. <ref name = 'Rich'>PMID:12838348</ref> <ref name ='Wang'>PMID:17485386</ref> ` | Z-DNA can form ''invitro'' from B-DNA by raising negative super helical stress or under physiological salt conditions when deoxycytosine is 5-methylated. The formation of Z-DNA which requires energy is an active process ''invivo''. A mechanism for initiation of Z-DNA involves formation of negative supercoils behind a moving RNA polymerase when it moves through DNA double helix. <ref name = 'Rich'>PMID:12838348</ref><ref name ='Wang'>PMID:17485386</ref> ` | ||
== Z-DNA binding proteins == | == Z-DNA binding proteins == | ||
