3ggu: Difference between revisions

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{{Seed}}
[[Image:3ggu.png|left|200px]]
[[Image:3ggu.jpg|left|200px]]


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==About this Structure==
==About this Structure==
3GGU is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GGU OCA].  
[[3ggu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GGU OCA].  


==Reference==
==Reference==
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[[Category: Rezacova, P.]]
[[Category: Rezacova, P.]]
[[Category: Saskova, K G.]]
[[Category: Saskova, K G.]]
[[Category: Darunvir]]
[[Category: Hiv protease]]
[[Category: Hydrolase]]
[[Category: Mutation score]]
[[Category: Resistance]]
[[Category: Tmc-114]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 12:35:34 2009''

Revision as of 04:46, 16 February 2011

File:3ggu.png


Drag the structure with the mouse to rotate
3ggu, resolution 1.80Å (default scene)
Ligands: 017
Gene: Gag-Pol, pol (Viruses)
Activity: HIV-1 retropepsin, with EC number 3.4.23.16
Related: 3ggt
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



HIV PR drug resistant patient's variant in complex with darunavir

Template:ABSTRACT PUBMED 19535439

About this Structure

3ggu is a 2 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

Reference

  1. Saskova KG, Kozisek M, Rezacova P, Brynda J, Yashina T, Kagan RM, Konvalinka J. Molecular characterization of clinical isolates of human immunodeficiency virus resistant to the protease inhibitor darunavir. J Virol. 2009 Sep;83(17):8810-8. Epub 2009 Jun 17. PMID:19535439 doi:10.1128/JVI.00451-09

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