3e51: Difference between revisions
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[[Image:3e51.png|left|200px]] | |||
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{{STRUCTURE_3e51| PDB=3e51 | SCENE= }} | {{STRUCTURE_3e51| PDB=3e51 | SCENE= }} | ||
===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor=== | ===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor=== | ||
{{ABSTRACT_PUBMED_18796353}} | {{ABSTRACT_PUBMED_18796353}} | ||
==About this Structure== | ==About this Structure== | ||
[[3e51]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E51 OCA]. | |||
==See Also== | |||
*[[RNA polymerase|RNA polymerase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018796353</ref><references group="xtra"/> | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
[[Category: Viruses]] | [[Category: Viruses]] | ||
| Line 36: | Line 27: | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 04:59, 27 July 2012
Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor
Template:ABSTRACT PUBMED 18796353
About this Structure
3e51 is a 2 chain structure of RNA polymerase with sequence from Viruses. Full crystallographic information is available from OCA.
See Also
Reference
- Dragovich PS, Blazel JK, Ellis DA, Han Q, Kamran R, Kissinger CR, LeBrun LA, Li LS, Murphy DE, Noble M, Patel RA, Ruebsam F, Sergeeva MV, Shah AM, Showalter RE, Tran CV, Tsan M, Webber SE, Kirkovsky L, Zhou Y. Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)- 5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5635-9. Epub 2008 Aug 29. PMID:18796353 doi:10.1016/j.bmcl.2008.08.094
