3hhk: Difference between revisions

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[[Image:3hhk.jpg|left|200px]]
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===HCV NS5b polymerase complex with a substituted benzothiadizine===
===HCV NS5b polymerase complex with a substituted benzothiadizine===
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{{ABSTRACT_PUBMED_19515564}}


==About this Structure==
==About this Structure==
3HHK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHK OCA].  
[[3hhk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HHK OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:19515564</ref><references group="xtra"/>
<ref group="xtra">PMID:019515564</ref><references group="xtra"/>
[[Category: Hepatitis c virus subtype 1b]]
[[Category: Hepatitis c virus subtype 1b]]
[[Category: Concha, N O.]]
[[Category: Concha, N O.]]
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[[Category: Helicase]]
[[Category: Helicase]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase/hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Inhhibitor]]
[[Category: Inhhibitor]]
[[Category: Membrane]]
[[Category: Membrane]]
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[[Category: Rna replication]]
[[Category: Rna replication]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep  9 09:26:33 2009''

Revision as of 10:52, 13 March 2013

Template:STRUCTURE 3hhk

HCV NS5b polymerase complex with a substituted benzothiadizine

Template:ABSTRACT PUBMED 19515564

About this Structure

3hhk is a 2 chain structure with sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.

Reference

  1. Shaw AN, Tedesco R, Bambal R, Chai D, Concha NO, Darcy MG, Dhanak D, Duffy KJ, Fitch DM, Gates A, Johnston VK, Keenan RM, Lin-Goerke J, Liu N, Sarisky RT, Wiggall KJ, Zimmerman MN. Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4350-3. Epub 2009 May 28. PMID:19515564 doi:10.1016/j.bmcl.2009.05.091

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