Sandbox 32

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D load='1a4v' size='350' frame='false' scene=
1a4v, resolution 1.80Å (default scene)
Ligands:	CA
Activity:	Lactose synthase, with EC number 2.4.1.22
Structural annotation: Resources: CATH : 1A4V000 InterPro : Ipr000545, Ipr001916 Pfam : PF00062 SCOP : d1a4v__ UniProt : P00709
Functional annotation: Cellular component: extracellular region extracellular space Biological process: signal transduction lactose biosynthetic process cell-cell signaling defense response to bacterium induction of apoptosis Molecular function: lactose synthase activity calcium ion binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Lactalbumin secondary structure This model shows the secondary structure of 1a4v. Alpha helices are shown as magenta rockets and beta sheets are shown as yellow arrows. Notice the beta sheets are running in opposite directions. (anti-parallel).

Lactalbumin Polar and Non polar groups This model shows the polar regions (charged or uncharged) in pink and the nonpolar regions in gray. Notice the polar groups are mostly on the outside while the non polar groups are clumped together and are mostly internal. Having the non polar groups together on the interior is more energetically efficient.

Lactalbumin ligands with their contacting molecules This model shows the two ligands on 1a4v and their surrounding molecules. The two ligands are composed of Calcium.

Lactalbumin charged residues This model shows the charged residues of 1a4v. Cations are blue, anions are red, and polar but uncharged side chains are light purple.

Lactalbumin amino and carboxy terminals The blue end of this model signifies the amino terminus of the protein (5' ends of the nucleic acid) and the red end signifies the carboxy terminus of the protein (3' end of the nucleic acid).