3jqa: Difference between revisions
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===Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-1,9-dihydro-6H-purine-6-thione (DX4)=== | |||
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{{ABSTRACT_PUBMED_19916554}} | |||
==About this Structure== | |||
3JQA is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQA OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:19916554</ref><references group="xtra"/> | |||
[[Category: Pteridine reductase]] | |||
[[Category: Trypanosoma brucei]] | |||
[[Category: Hunter, W N.]] | |||
[[Category: Tulloch, L B.]] | |||
[[Category: Inhibitor]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Pteridine reductase]] | |||
[[Category: Ptr1]] | |||
[[Category: Short chain dehydrogenase]] | |||
[[Category: Trypanosoma brucei]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 15:03:39 2009'' | |||
Revision as of 13:03, 9 December 2009
Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-1,9-dihydro-6H-purine-6-thione (DX4)
Template:ABSTRACT PUBMED 19916554
About this Structure
3JQA is a 4 chains structure of sequences from Trypanosoma brucei. Full crystallographic information is available from OCA.
Reference
- Tulloch LB, Martini VP, Iulek J, Huggan JK, Lee JH, Gibson CL, Smith TK, Suckling CJ, Hunter WN. Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases. J Med Chem. 2009 Nov 16. PMID:19916554 doi:10.1021/jm901059x
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