Ribosome: Difference between revisions
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'''The Ribosome'''<br | '''The Ribosome'''<br> | ||
'''The protein synthesis machine of cells shown with the 3 tRNAs and messenger RNA bound.''' | '''The protein synthesis machine of cells''' <br> | ||
'''shown with the 3 tRNAs and messenger RNA bound.''' | |||
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The particular structures for which the prize was awarded were published in 2000 and were subsequently refined or improved upon: | The particular structures for which the prize was awarded were published in 2000 and were subsequently refined or improved upon: | ||
Yonath lab structures: [[1fka]], improved in [[1i94]] [[1i95]] [[1i96]] [[1i97]] | Yonath lab structures: [[1fka]], improved in [[1i94]] [[1i95]] [[1i96]] [[1i97]]<br> | ||
Ramakrishnan lab structures: [[1fjf]] which was later refine to [[1j5e]] | Ramakrishnan lab structures: [[1fjf]] which was later refine to [[1j5e]] | ||
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==Additional Structures== | ==Additional Structures== | ||
Several other ribosome structures have now been published, and here are just a few of the significant ones:<br> | Several other ribosome structures have now been published, and here are just a few of the significant ones:<br> | ||
[[2j00]] and [[2j01]] are the subunits of the 70S ribosome structure. | [[2j00]] and [[2j01]] are the subunits of the 70S ribosome structure.<br> | ||
[[1gix]] and [[1giy]] are the subunits of the 70S ribosome structure determined by the Noller lab. | [[1gix]] and [[1giy]] are the subunits of the 70S ribosome structure determined by the Noller lab.<br> | ||
[[2i2u]] and [[2i2v]] are the subunits of the E. coli ribosome at 3.2 Å. | [[2i2u]] and [[2i2v]] are the subunits of the E. coli ribosome at 3.2 Å.<br> | ||
[[2gya]] and [[2gy9]] are the subunits of a complete E. coli ribosome as determined by cryo-EM by Joachim Frank's lab. | [[2gya]] and [[2gy9]] are the subunits of a complete E. coli ribosome as determined by cryo-EM by Joachim Frank's lab.<br> | ||