Ribosome: Difference between revisions

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'''The Ribosome'''<br />
'''The Ribosome'''<br>
'''The protein synthesis machine of cells shown with the 3 tRNAs and messenger RNA bound.'''
'''The protein synthesis machine of cells''' <br>
'''shown with the 3 tRNAs and messenger RNA bound.'''




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The particular structures for which the prize was awarded were published in 2000 and were subsequently refined or improved upon:
The particular structures for which the prize was awarded were published in 2000 and were subsequently refined or improved upon:


Yonath lab structures: [[1fka]], improved in [[1i94]] [[1i95]] [[1i96]] [[1i97]]
Yonath lab structures: [[1fka]], improved in [[1i94]] [[1i95]] [[1i96]] [[1i97]]<br>


Ramakrishnan lab structures: [[1fjf]] which was later refine to [[1j5e]]
Ramakrishnan lab structures: [[1fjf]] which was later refine to [[1j5e]]
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==Additional Structures==
==Additional Structures==
Several other ribosome structures have now been published, and here are just a few of the significant ones:<br>
Several other ribosome structures have now been published, and here are just a few of the significant ones:<br>
[[2j00]] and [[2j01]] are the subunits of the 70S ribosome structure.
[[2j00]] and [[2j01]] are the subunits of the 70S ribosome structure.<br>
[[1gix]] and [[1giy]] are the subunits of the 70S ribosome structure determined by the Noller lab.
[[1gix]] and [[1giy]] are the subunits of the 70S ribosome structure determined by the Noller lab.<br>
[[2i2u]] and [[2i2v]] are the subunits of the E. coli ribosome at 3.2 &Aring;.
[[2i2u]] and [[2i2v]] are the subunits of the E. coli ribosome at 3.2 &Aring;.<br>
[[2gya]] and [[2gy9]] are the subunits of a complete E. coli ribosome as determined by cryo-EM by Joachim Frank's lab.
[[2gya]] and [[2gy9]] are the subunits of a complete E. coli ribosome as determined by cryo-EM by Joachim Frank's lab.<br>