User:Eleanor Crabb/Sandbox 2: Difference between revisions

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Protein structure
Protein structure


Returning now to both chains in the structure 1z3a we will use this to identify the four tiers of protein structure.<applet load='1z3a' size='300' frame='true' align='right' caption='Insert caption here' /><scene name='User:Eleanor_Crabb/Sandbox_2/1z3a_chaina/1'> the amino acid residue</scene>
Returning now to both chains in the structure '''1z3a''' we will use this to identify the four tiers of protein structure.<applet load='1z3a' size='300' frame='true' align='right' caption='Insert caption here' /><scene name='User:Eleanor_Crabb/Sandbox_2/1z3a_chaina/1'> the amino acid residue</scene>
The '''primary structure''' is simply the arrangement of amino acid residues with in the chain. This can be emphasized by colouring Chain A according to <scene name='User:Eleanor_Crabb/Sandbox_2/1z3a_chaina_amino/1'>residue</scene>. Hover your cursor over the molecule to identify some of the different residues present in the protein.
The '''primary structure''' is simply the arrangement of amino acid residues with in the chain. This can be emphasized by colouring Chain A according to <scene name='User:Eleanor_Crabb/Sandbox_2/1z3a_chaina_amino/1'>residue</scene>. Hover your cursor over the molecule to identify some of the different residues present in the protein.


The protein can also be coloured according to the '''secondary structure'''. In the <scene name='User:Eleanor_Crabb/Sandbox_2/1z3a_chaina_secondarystructure/1'>secondary structure</scene> a-helices are shown in pink and <math>b</math>-sheets in yellow. Rotate the molecule to look at these features in more detail.
The protein can also be coloured according to the '''secondary structure'''. The <scene name='User:Eleanor_Crabb/Sandbox_2/1z3a_chaina_secondarystructure/1'>secondary structure</scene>here are the alpha-helices shown in pink, beta-sheets in yellow, with the interconnecting loops in white. Rotate the molecule to look at these features in more detail. If we now consider just the <scene name='User:Eleanor_Crabb/Sandbox_2/1z3a_chaina_hbonds/1'>backbone with hydrogen bonds</scene> we can see how this secondary structure is held together by hydrogen bonds.
 
As an enzyme, this protein is an example of a globular protein as we can see when consider the space-filled representation of the entire protein, both chains A and B. This the tertiary structure of the protein.
 
Finally, the quaternary structure here refers . In this particular example