3juh: Difference between revisions
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New page: '''Unreleased structure''' The entry 3juh is ON HOLD Authors: Niefind, K., Issinger, O.-G. Description: Crystal structure of a mutant of human protein kinase CK2alpha with altered cosu... |
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===Crystal structure of a mutant of human protein kinase CK2alpha with altered cosubstrate specificity=== | |||
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==About this Structure== | |||
3JUH is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entries and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ymi 1ymi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUH OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:18291315</ref><ref group="xtra">PMID:15740749</ref><ref group="xtra">PMID:19693436</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Non-specific serine/threonine protein kinase]] | |||
[[Category: Issinger, O G.]] | |||
[[Category: Niefind, K.]] | |||
[[Category: Atp-binding]] | |||
[[Category: Eukaryotic protein kinase]] | |||
[[Category: Kinase]] | |||
[[Category: Nucleotide-binding]] | |||
[[Category: Phosphoprotein]] | |||
[[Category: Serine/threonine-protein kinase]] | |||
[[Category: Transferase]] | |||
[[Category: Wnt signaling pathway]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:09:55 2009'' | |||
Revision as of 08:10, 21 October 2009
Crystal structure of a mutant of human protein kinase CK2alpha with altered cosubstrate specificity
Template:ABSTRACT PUBMED 18291315
About this Structure
3JUH is a 2 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entries and 1ymi. Full crystallographic information is available from OCA.
Reference
- Raaf J, Brunstein E, Issinger OG, Niefind K. The CK2 alpha/CK2 beta interface of human protein kinase CK2 harbors a binding pocket for small molecules. Chem Biol. 2008 Feb;15(2):111-7. PMID:18291315 doi:https://dx.doi.org/10.1016/j.chembiol.2007.12.012
- Yde CW, Ermakova I, Issinger OG, Niefind K. Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate. J Mol Biol. 2005 Mar 25;347(2):399-414. Epub 2005 Jan 18. PMID:15740749 doi:https://dx.doi.org/10.1016/j.jmb.2005.01.003
- PMID: https://pubmed.ncbi.nlm.nih.gov/19693436/
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