3jz2: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3jz2.jpg|left|200px]]


The entry 3jz2 is ON HOLD until Paper Publication
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{{STRUCTURE_3jz2|  PDB=3jz2  |  SCENE=  }}


Authors: Niu, W., Chen, Z., Bush-Pelc, L.A., Bah, A., Gandhi, P.S., Di Cera, E.
===Crystal structure of human thrombin mutant N143P in E* form===


Description: Crystal structure of human thrombin mutant N143P in E* form


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:44:20 2009''
==Disease==
Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
 
==About this Structure==
3JZ2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JZ2 OCA].
 
==Reference==
<ref group="xtra">PMID:18250335</ref><ref group="xtra">PMID:15152000</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Bah, A.]]
[[Category: Bush-Pelc, L A.]]
[[Category: Cera, E Di.]]
[[Category: Chen, Z.]]
[[Category: Gandhi, P S.]]
[[Category: Niu, W.]]
[[Category: Acute phase]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Disulfide bond]]
[[Category: Gamma-carboxyglutamic acid]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Kringle]]
[[Category: Pharmaceutical]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Zymogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:42:36 2009''

Revision as of 08:42, 21 October 2009

File:3jz2.jpg

Template:STRUCTURE 3jz2

Crystal structure of human thrombin mutant N143P in E* form

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

3JZ2 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Gandhi PS, Chen Z, Mathews FS, Di Cera E. Structural identification of the pathway of long-range communication in an allosteric enzyme. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:18250335
  2. Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:https://dx.doi.org/10.1074/jbc.M401756200

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