2vx1: Difference between revisions

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==About this Structure==
==About this Structure==
2VX1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX1 OCA].  
2VX1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX1 OCA].  


==Reference==
==Reference==
Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines., Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ, Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18434142 18434142]
<ref group="xtra">PMID:18434142</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Single protein]]
[[Category: Barratt, D.]]
[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
[[Category: Brassington, C A.]]
[[Category: Green, I.]]
[[Category: Kettle, J G.]]
[[Category: Leach, A G.]]
[[Category: Mccall, E J.]]
[[Category: Read, J.]]
[[Category: Valentine, A L.]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
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[[Category: Unphosphorylated]]
[[Category: Unphosphorylated]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 25 20:14:13 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 20:14:52 2009''

Revision as of 18:05, 11 November 2009

File:2vx1.png

Template:STRUCTURE 2vx1

EPHB4 KINASE DOMAIN INHIBITOR COMPLEX

Template:ABSTRACT PUBMED 18434142

About this Structure

2VX1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines. Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:18434142 doi:10.1016/j.bmcl.2008.04.015

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