Sandbox122: Difference between revisions
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[[Image:1G28.pdb b.jpg | thumb]] STRUCTURE OF A FLAVIN-BINDING DOMAIN, LOV2, FROM THE CHIMERIC PHYTOCHROME/PHOTOTROPIN PHOTORECEPTOR PHY3 {{STRUCTURE_1g28| PDB=1g28 | SCENE= }} | |||
STRUCTURE OF A FLAVIN-BINDING DOMAIN, LOV2, FROM THE CHIMERIC PHYTOCHROME/PHOTOTROPIN PHOTORECEPTOR PHY3 | |||
{{STRUCTURE_1g28| PDB=1g28 | SCENE= }} | |||
'''Phototropin''' is a blue light receptor involved in the phototropism (it is a phenomenon which is growth directed by light).This is a transmembrane protein present on the top of coleoptile. | '''Phototropin''' is a blue light receptor involved in the phototropism (it is a phenomenon which is growth directed by light).This is a transmembrane protein present on the top of coleoptile. | ||
This protein is a dimer (phot1 and phot2) and each subunit contains three domains : LOV1, '''LOV2''' (light,oxygen or voltage) domains and a kinase domain. | This protein is a dimer (phot1 and phot2) and each subunit contains three domains : LOV1, '''LOV2''' (light,oxygen or voltage) domains and a kinase domain. | ||
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For more information about the continuation of this mechanism refer to this PDB protein: 2z6c,2z6d, | For more information about the continuation of this mechanism refer to this PDB protein: 2z6c,2z6d, | ||
==Reference and tools== | ==Reference and tools== | ||
John T. M. Kennis, Ivo H. M. van Stokkum, Sean Crosson, Magdalena Gauden, Keith Moffat, and Rienk van Grondelle:The LOV2 Domain of Phototropin: A Reversible Photochromic Switch.J. Am. Chem. Soc., 2004, 126 (14), pp 4512–4513 | .John T. M. Kennis, Ivo H. M. van Stokkum, Sean Crosson, Magdalena Gauden, Keith Moffat, and Rienk van Grondelle:The LOV2 Domain of Phototropin: A Reversible Photochromic Switch.J. Am. Chem. Soc., 2004, 126 (14), pp 4512–4513. | ||
.Maxime T. A. Alexandre, Jos C. Arents, Rienk van Grondelle, Klaas J. Hellingwerf, and John T. M. Kennis:A Base-Catalyzed Mechanism for Dark State Recovery in the Avena sativa Phototropin-1 LOV2 Domain. Biochemistry, 2007, 46 (11), pp 3129–3137. | |||
.Crosson S, Moffat KStructure of a flavin-binding plant photoreceptor domain: insights into light-mediated signal transductionProc. Natl. Acad. Sci. U. S. A. v98, p.2995-3000. | |||
software used: pymol, chemstek | software used: pymol, chemstek | ||
==Proteopedia Page Contributors and editors== | ==Proteopedia Page Contributors and editors== | ||
David Bauché | David Bauché | ||
