Sandbox136: Difference between revisions
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Elie Peillon (talk | contribs) No edit summary |
Elie Peillon (talk | contribs) No edit summary |
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+O4 atom whit K53 Nζ and R34 Nη2 | +O4 atom whit K53 Nζ and R34 Nη2 | ||
[[Image:Anion_Interactions.jpg ]] | [[Image:Anion_Interactions.jpg | thumb]] | ||
This anion-binding site is supposed to play a role in the fixation of inhibitors but his function remains unknown. In the crystallization state (pH5), the protein is in a monomer state whereas in a solution at physiological pH, a dimerization occurs . The dimerization happened thanks to interactions at the interface of the N-terminal and β-wing regions . Studies have shown that Lys49 PLA2 is active only in the dimer state | This anion-binding site is supposed to play a role in the fixation of inhibitors but his function remains unknown. In the crystallization state (pH5), the protein is in a monomer state whereas in a solution at physiological pH, a dimerization occurs . The dimerization happened thanks to interactions at the interface of the N-terminal and β-wing regions . Studies have shown that Lys49 PLA2 is active only in the dimer state | ||
