Sandbox129: Difference between revisions
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PTS have two functions in organisms, the first one is the control of sugar consumption, the second one is the control of the carbon metabolism. PTS is composed of four phosphoproteins, whose aim is to regulate the transfer of a phosphyl group from phosphoenolpyruvate (PEP) to sugar which can then move into the cell. PEP is the phosphate stock in this system. The phosphate transfer occurs by five phosphorylation steps : | |||
-PEP binds on the PEP binding domain of the C terminal domain of EI (EIC) | -PEP binds on the PEP binding domain of the C terminal domain of EI (EIC) | ||
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-Enzyme II (EII) have three functional units : the first unit EIIA receives phosphate from HPr, transfers it to the second unit EIIB, then the third unit EIIC allows the transfer of the phosphoryl group from EIIB to the sugar. | -Enzyme II (EII) have three functional units : the first unit EIIA receives phosphate from HPr, transfers it to the second unit EIIB, then the third unit EIIC allows the transfer of the phosphoryl group from EIIB to the sugar. | ||
In vivo, the transferred phosphate come from PEP, but in vivo it can come from ATP or acetyl phosphate too. | In vivo, the transferred phosphate come from PEP, but in vivo it can come from ATP or acetyl phosphate too. | ||
== II. Structure of Enzyme I == | == II. Structure of Enzyme I == | ||
