Sandbox129: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 47: Line 47:
== III.Staphylococcus aureus vs Escherichia coli ==
== III.Staphylococcus aureus vs Escherichia coli ==


[[Image:Saureus ok.jpg]][[Image:Ecoli ok.jpg]]
[[Image:Saureus ok.jpg]]
 
[[Image:Ecoli ok.jpg]]


The X-ray structure of S. aureus EI (SaEI) has been recently solved but structures of other bacterias have been reported before, for instance E. coli EI structure (EcEI). Although SaEI and EcEI X-ray structures are nearly the same, some differences have been observed.
The X-ray structure of S. aureus EI (SaEI) has been recently solved but structures of other bacterias have been reported before, for instance E. coli EI structure (EcEI). Although SaEI and EcEI X-ray structures are nearly the same, some differences have been observed.
Line 64: Line 66:
Knowing the structure of S. aureus EI allows a better comprehension of the PTS mechanism. But progresses could be still done such as the possible phenomena which induce the motions of the different domains.
Knowing the structure of S. aureus EI allows a better comprehension of the PTS mechanism. But progresses could be still done such as the possible phenomena which induce the motions of the different domains.


Reference
 
== Reference ==
 
Oberholzer AE, Schneider P, Siebold C, Baumann U, Erni B. (2009).Crystal structure of enzyme I of the phosphoenolpyruvate:Sugar phosphotransferase system in the dephosphorylated state. J Biol Chem
Oberholzer AE, Schneider P, Siebold C, Baumann U, Erni B. (2009).Crystal structure of enzyme I of the phosphoenolpyruvate:Sugar phosphotransferase system in the dephosphorylated state. J Biol Chem
PMID: 19801641
PMID: 19801641


3D Structures of EI
==
3D Structures of EI ==
 
[http://www.pdb.org/pdb/explore/explore.do?structureId=2WQD 2wqd] S. aureus EI phosphorylated structure
[http://www.pdb.org/pdb/explore/explore.do?structureId=2WQD 2wqd] S. aureus EI phosphorylated structure
[http://www.pdb.org/pdb/explore/explore.do?structureId=2HWG 2hwg] E. coli phosphorylated and Mg2+-oxalate bound structure
[http://www.pdb.org/pdb/explore/explore.do?structureId=2HWG 2hwg] E. coli phosphorylated and Mg2+-oxalate bound structure


Links
 
== Links ==
 
Proteopedia page[http://www.proteopedia.org/wiki/index.php/Enzyme_I_of_the_Phosphoenolpyruvate:Sugar_Phosphotransferase_System Proteopedia page] : Enzyme I of the Phosphoenolpyruvate:Sugar Phosphotransferase System (E. coli and S. carnosus)
Proteopedia page[http://www.proteopedia.org/wiki/index.php/Enzyme_I_of_the_Phosphoenolpyruvate:Sugar_Phosphotransferase_System Proteopedia page] : Enzyme I of the Phosphoenolpyruvate:Sugar Phosphotransferase System (E. coli and S. carnosus)