3k9x: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3k9x.jpg|left|200px]]


The entry 3k9x is ON HOLD until Paper Publication
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{{STRUCTURE_3k9x|  PDB=3k9x  |  SCENE=  }}


Authors: Klei, H.E., Kish, K., Ghosh, K., Rushith, A.
===X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE===


Description: X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2-(PYRROLIDIN-1-YL)ETHYL)AZEPAN-3-YLAMINO)METHYLENE)NICOTINAMIDE


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==About this Structure==
3K9X is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K9X OCA].
 
==Reference==
<ref group="xtra">PMID:19896847</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Ghosh, K.]]
[[Category: Kish, K.]]
[[Category: Klei, H E.]]
[[Category: Rushith, A.]]
[[Category: Blood clotting]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation factor]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disulfide bond]]
[[Category: Egf-like domain]]
[[Category: Epidermal growth factor like domain]]
[[Category: Gamma-carboxyglutamic acid]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Hydroxylation]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Zymogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 16 13:09:13 2009''

Revision as of 11:09, 16 December 2009

File:3k9x.jpg

Template:STRUCTURE 3k9x

X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE

Template:ABSTRACT PUBMED 19896847

About this Structure

3K9X is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Shi Y, Li C, O'Connor SP, Zhang J, Shi M, Bisaha SN, Wang Y, Sitkoff D, Pudzianowski AT, Huang C, Klei HE, Kish K, Yanchunas J Jr, Liu EC, Hartl KS, Seiler SM, Steinbacher TE, Schumacher WA, Atwal KS, Stein PD. Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6882-9. Epub 2009 Oct 23. PMID:19896847 doi:10.1016/j.bmcl.2009.10.084

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