User:Wayne Decatur/SandboxRibosome: Difference between revisions
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THIS IS THE OCTOBER 15th version of the page I had made for Proteopedia Ribosome page with other parts I am working on to add to that current page | |||
==Background== | ==Background== | ||
Venkatraman Ramakrishnan of the M.R.C. Laboratory of Molecular Biology in Cambridge, England; Thomas A. Steitz of Yale University; and Ada E. Yonath of the Weizmann Institute of Science in Rehovot, Israel are being awarded the [http://nobelprize.org/nobel_prizes/chemistry/laureates/2009/ the 2009 Nobel Prize in Chemistry] for their for their landmark work revealing the atomic details of the molecular machine that make proteins in all cells, [http://en.wikipedia.org/wiki/ribosome the ribosome]. This work was the gloriously enlightening culmination of years of work, first heralded by Ada Yonath's report of crystals in 1980. Others made significant contributions to the detailed structure of this machine, as poignantly summarized by [https://loop.nigms.nih.gov/index.php/2009/10/07/2009-chemistry-nobel-prize-recognizes-the-determination-of-the-ribosomes-three-dimensional-structure/ Jeremy Berg, current Director of National Institute of General Medical Sciences, in his announcement], "The Nobel committee has the daunting challenge of limiting itself to up to three laureates for each prize. Several other long-time NIGMS grantees who also contributed greatly to our understanding of the structure and function of the ribosome include Peter Moore, Harry Noller and Joachim Frank." The American Society for Biochemistry and Molecular Biology posted [http://www.asbmb.org/News.aspx?id=3612 an announcement of the prize echoing this sentiment] as well.<br> | Venkatraman Ramakrishnan of the M.R.C. Laboratory of Molecular Biology in Cambridge, England; Thomas A. Steitz of Yale University; and Ada E. Yonath of the Weizmann Institute of Science in Rehovot, Israel are being awarded the [http://nobelprize.org/nobel_prizes/chemistry/laureates/2009/ the 2009 Nobel Prize in Chemistry] for their for their landmark work revealing the atomic details of the molecular machine that make proteins in all cells, [http://en.wikipedia.org/wiki/ribosome the ribosome]. This work was the gloriously enlightening culmination of years of work, first heralded by Ada Yonath's report of crystals in 1980. Others made significant contributions to the detailed structure of this machine, as poignantly summarized by [https://loop.nigms.nih.gov/index.php/2009/10/07/2009-chemistry-nobel-prize-recognizes-the-determination-of-the-ribosomes-three-dimensional-structure/ Jeremy Berg, current Director of National Institute of General Medical Sciences, in his announcement], "The Nobel committee has the daunting challenge of limiting itself to up to three laureates for each prize. Several other long-time NIGMS grantees who also contributed greatly to our understanding of the structure and function of the ribosome include Peter Moore, Harry Noller and Joachim Frank." The American Society for Biochemistry and Molecular Biology posted [http://www.asbmb.org/News.aspx?id=3612 an announcement of the prize echoing this sentiment] as well.<br> | ||
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*Structural basis of a mechanism of hydrolytic release of the newly formed polypeptide by the large subunit that may be analogous to that used by release factors:[[3cma]], [[3cme]] | *Structural basis of a mechanism of hydrolytic release of the newly formed polypeptide by the large subunit that may be analogous to that used by release factors:[[3cma]], [[3cme]] | ||
*Elongation factor P bound to the 70S ribosome: [[3huw]], [[3hux]], [[3huy]], [[3huz]].<br> | *Elongation factor P bound to the 70S ribosome: [[3huw]], [[3hux]], [[3huy]], [[3huz]].<br> | ||
== | |||
==Scenes introducing the Ribosome== | |||
<scene name='User:Wayne_Decatur/SandboxRibosome/Bothmodels6/1'>The 70S ribosome</scene><br> | <scene name='User:Wayne_Decatur/SandboxRibosome/Bothmodels6/1'>The 70S ribosome</scene><br> | ||
Three tRNAs and an mRNA are bound. | Three tRNAs and an mRNA are bound. | ||
