3jsw: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
3JSW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSW OCA]. | 3JSW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSW OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:19919087</ref><references group="xtra"/> | |||
[[Category: 3',5'-cyclic-GMP phosphodiesterase]] | [[Category: 3',5'-cyclic-GMP phosphodiesterase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 23 09:04:17 2009'' | ||
Revision as of 07:04, 23 December 2009
Human PDE9 in complex with selective inhibitor
About this Structure
3JSW is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Verhoest PR, Proulx-Lafrance C, Corman M, Chenard L, Helal CJ, Hou X, Kleiman R, Liu S, Marr E, Menniti FS, Schmidt CJ, Vanase-Frawley M, Schmidt AW, Williams RD, Nelson FR, Fonseca KR, Liras S. Identification of a brain penetrant PDE9A inhibitor utilizing prospective design and chemical enablement as a rapid lead optimization strategy. J Med Chem. 2009 Dec 24;52(24):7946-9. PMID:19919087 doi:10.1021/jm9015334
Page seeded by OCA on Wed Dec 23 09:04:17 2009
