3kga: Difference between revisions
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{{STRUCTURE_3kga| PDB=3kga | SCENE= }} | |||
===Crystal structure of MAPKAP kinase 2 (MK2) complexed with a potent 3-aminopyrazole ATP site inhibitor=== | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | <!-- | ||
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{{ABSTRACT_PUBMED_20060294}} | |||
==About this Structure== | |||
3KGA is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KGA OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:20060294</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Non-specific serine/threonine protein kinase]] | |||
[[Category: Be, C.]] | |||
[[Category: Huppertz, C.]] | |||
[[Category: Izaac, A.]] | |||
[[Category: Kroemer, M.]] | |||
[[Category: Pflieger, D.]] | |||
[[Category: Scheufler, C.]] | |||
[[Category: Schlapbach, A.]] | |||
[[Category: Velcicky, J.]] | |||
[[Category: 3-aminopyrazole scaffold]] | |||
[[Category: Activation loop deletion]] | |||
[[Category: Alternative splicing]] | |||
[[Category: Atp-binding]] | |||
[[Category: Atp-site kinase inhibitor]] | |||
[[Category: Induced fit]] | |||
[[Category: Kinase]] | |||
[[Category: Novel hydrophobic pocket]] | |||
[[Category: Nucleotide-binding]] | |||
[[Category: Phosphoprotein]] | |||
[[Category: Polymorphism]] | |||
[[Category: Scaffold hoping]] | |||
[[Category: Serine/threonine-protein kinase]] | |||
[[Category: Small molecule inhibitor]] | |||
[[Category: Transferase]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:45:42 2010'' | |||
Revision as of 17:45, 27 January 2010
Crystal structure of MAPKAP kinase 2 (MK2) complexed with a potent 3-aminopyrazole ATP site inhibitor
Template:ABSTRACT PUBMED 20060294
About this Structure
3KGA is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Velcicky J, Feifel R, Hawtin S, Heng R, Huppertz C, Koch G, Kroemer M, Moebitz H, Revesz L, Scheufler C, Schlapbach A. Novel 3-aminopyrazole inhibitors of MK-2 discovered by scaffold hopping strategy. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1293-7. Epub 2009 Nov 3. PMID:20060294 doi:10.1016/j.bmcl.2009.10.138
Page seeded by OCA on Wed Jan 27 19:45:42 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Be, C.
- Huppertz, C.
- Izaac, A.
- Kroemer, M.
- Pflieger, D.
- Scheufler, C.
- Schlapbach, A.
- Velcicky, J.
- 3-aminopyrazole scaffold
- Activation loop deletion
- Alternative splicing
- Atp-binding
- Atp-site kinase inhibitor
- Induced fit
- Kinase
- Novel hydrophobic pocket
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Scaffold hoping
- Serine/threonine-protein kinase
- Small molecule inhibitor
- Transferase
