3iw4: Difference between revisions

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{{Seed}}
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[[Image:3iw4.jpg|left|200px]]
[[Image:3iw4.png|left|200px]]


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==About this Structure==
==About this Structure==
3IW4 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IW4 OCA].  
3IW4 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IW4 OCA].  


==Reference==
==Reference==
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[[Category: Zinc-finger]]
[[Category: Zinc-finger]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov  4 11:01:42 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:38:38 2010''

Revision as of 12:38, 28 January 2010

File:3iw4.png

Template:STRUCTURE 3iw4

Crystal structure of PKC alpha in complex with NVP-AEB071

Template:ABSTRACT PUBMED 19827831

About this Structure

3IW4 is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Wagner J, von Matt P, Sedrani R, Albert R, Cooke N, Ehrhardt C, Geiser M, Rummel G, Stark W, Strauss A, Cowan-Jacob SW, Beerli C, Weckbecker G, Evenou JP, Zenke G, Cottens S. Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5 -dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes. J Med Chem. 2009 Oct 22;52(20):6193-6. PMID:19827831 doi:10.1021/jm901108b

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