Group:SMART:2010 Pingry SMART Team: Difference between revisions

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====PDB ID: 1mi3, Xylose reductase with NAD+====
====PDB ID: 1mi3, Xylose reductase with NAD+====
As with the previous protein, pink and blue highlight the alpha and beta barrel structure common to AKR's.  The cofactor NAD+ is shown in wireframe and colored CPK.
While xylose reductase prefers to utilize NADP+, it is able to accommodate the absence of the 2'-phosphate by adapting different conformations.  Asn276 shifts to Hydrogen bond