Retroviral Integrase: Difference between revisions
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==Impact of Structure== | ==Impact of Structure== | ||
HIV protease structure is among the highest ranked structures that have contributed to saving many lives and added to the quality of life of many HIV-afflicted individuals. It is implemented in [[Structure-based drug design|structure-based drug design]] to develop [http://en.wikipedia.org/wiki/ | HIV protease structure is among the highest ranked structures that have contributed to saving many lives and added to the quality of life of many HIV-afflicted individuals. It is implemented in [[Structure-based drug design|structure-based drug design]] to develop [http://en.wikipedia.org/wiki/Integrase_inhibitors antiretroviral integrase inhibitors], and is used as a significant component of . While existing therapies such as protease inhibitors and ''highly active anti-retroviral therapy'' ([http://en.wikipedia.org/wiki/Haart HAART])agents improve the quality of life as well as extending the life of many patients, it fails to eradicate the disease. For more, please see [[User:Eric_Martz/Molecular_Playground/HIVDrug|AIDS Before Protease Inhibitors & HIV Protease Inhibitors: A Breakthrough]]. | ||
==PFV Crystallization== | ==PFV Crystallization== | ||
