Group:SMART:2010 Pingry SMART Team: Difference between revisions
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Lys274 and Ser275 interact only with to the NADP+ cofactor and change positions (usually turn away) when NAD+ is present. | Lys274 and Ser275 interact only with to the NADP+ cofactor and change positions (usually turn away) when NAD+ is present. | ||
<scene name='2010_Pingry_SMART_Team/1k8c_default/5'>Lys274</scene> interacts with the 2-prime alcohol group on the NADP+ ribose but turns away and does not interact when NAD+ is the cofactor. <scene name='2010_Pingry_SMART_Team/1k8c_default/ | <scene name='2010_Pingry_SMART_Team/1k8c_default/5'>Lys274</scene> interacts with the 2-prime alcohol group on the NADP+ ribose but turns away and does not interact when NAD+ is the cofactor. <scene name='2010_Pingry_SMART_Team/1k8c_default/22'>Ser275</scene> | ||
interacts with an oxygen on the phosphate group on the ribose of NADP+ but similarly to the Lys274, does not interact with the NAD+ cofactor. | interacts with an oxygen on the phosphate group on the ribose of NADP+ but similarly to the Lys274, does not interact with the NAD+ cofactor. | ||