Phosphoglucoisomerase: Difference between revisions
From Proteopedia
Jump to navigationJump to search
| Line 25: | Line 25: | ||
The proposed reaction mechanism of PGI for the conversion of glucose-6-phosphate to fructose 6-phosphate involves an acid/base catalysis by the enzyme. | The proposed reaction mechanism of PGI for the conversion of glucose-6-phosphate to fructose 6-phosphate involves an acid/base catalysis by the enzyme. | ||
Step 1 The substrate binds to the enzyme. | |||
Step 2 The residue Lys518 or His388b acts as an enzymatic acid catalazyng the opening of the ring. | |||
[[Image:Mech.png]] | [[Image:Mech.png]] | ||
