Birrer Sandbox 2: Difference between revisions

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==Alcohol Dehydrogenase==
==Alcohol Dehydrogenase==
Alcohol dehydrogenase (ADH) is an enzyme that catalyzes the oxidation of primary and secondary alcohols to their corresponding aldehydes and ketones through a mechanism that involves the removal of hydrogen.  In the oxidation mechanism, ADH is momentarily associated with nicontinamide adenine dinucleotide (NAD+), which functions as a cosubstrate. The mechanism of the reaction is below:
Alcohol dehydrogenase (ADH) is an enzyme that catalyzes the oxidation of primary and secondary alcohols to their corresponding aldehydes and ketones through a mechanism that involves the removal of hydrogen.  In the oxidation mechanism, ADH is momentarily associated with nicontinamide adenine dinucleotide (NAD+), which functions as a cosubstrate. The mechanism of the reaction is below:
CH3CH2OH + NAD+ [[Image:arrow.jpg]] CH3COH (acetaldehyde) + NADH + H+
CH3CH2OH + NAD+ → CH3COH (acetaldehyde) + NADH + H+ (Note: The reaction is actually reversible although the arrow does not show it)




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and display another structure.
and display another structure.


{{STRUCTURE_3cin |  PDB=3cin |  SCENE=  }}
{{STRUCTURE_1htb |  PDB=1htb |  SCENE=  }}