3lc3: Difference between revisions

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{{Seed}}
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[[Image:3lc3.jpg|left|200px]]
[[Image:3lc3.png|left|200px]]


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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 13:27:22 2010''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  3 13:12:38 2010''

Revision as of 11:12, 3 March 2010

File:3lc3.png

Template:STRUCTURE 3lc3

Benzothiophene Inhibitors of Factor IXa

Template:ABSTRACT PUBMED 20121198

Disease

Known disease associated with this structure: Hemophilia B OMIM:[300746]

About this Structure

3LC3 is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Wang S, Beck R, Blench T, Burd A, Buxton S, Malic M, Ayele T, Shaikh S, Chahwala S, Chander C, Holland R, Merette S, Zhao L, Blackney M, Watts A. Studies of Benzothiophene Template as Potent Factor IXa (FIXa) Inhibitors in Thrombosis. J Med Chem. 2010 Feb 25;53(4):1465-72. PMID:20121198 doi:10.1021/jm901475e

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