3lc5: Difference between revisions
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Revision as of 12:22, 3 March 2010
Selective Benzothiophine Inhibitors of Factor IXa
Template:ABSTRACT PUBMED 20121197
Disease
Known disease associated with this structure: Hemophilia B OMIM:[300746]
About this Structure
3LC5 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wang S, Beck R, Burd A, Blench T, Marlin F, Ayele T, Buxton S, Dagostin C, Malic M, Joshi R, Barry J, Sajad M, Cheung C, Shaikh S, Chahwala S, Chander C, Baumgartner C, Holthoff HP, Murray E, Blackney M, Giddings A. Structure Based Drug Design: Development of Potent and Selective Factor IXa (FIXa) Inhibitors. J Med Chem. 2010 Feb 25;53(4):1473-82. PMID:20121197 doi:10.1021/jm901476x
Page seeded by OCA on Wed Mar 3 14:22:05 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor IXa
- Homo sapiens
- Beck, R.
- Wang, S.
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Disulfide bond
- Egf-like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hemophilia
- Hydrolase
- Hydrolase-hydrolase inhibitor complex
- Hydroxylation
- Peptidase s1
- Pharmaceutical
- Phosphoprotein
- Polymorphism
- Protease
- Protein-inhibitor complex
- Secreted
- Serine protease
- Sulfation
- Zymogen
