3ixj: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3ixj.jpg|left|200px]]


The entry 3ixj is ON HOLD until Paper Publication
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{{STRUCTURE_3ixj|  PDB=3ixj  |  SCENE=  }}


Authors: Borkakoti, N., Lindberg, J., Nystrom, S.
===Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor===


Description: Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:48:01 2009''
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{{ABSTRACT_PUBMED_20128595}}
 
==About this Structure==
3IXJ is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IXJ OCA].
 
==Reference==
<ref group="xtra">PMID:20128595</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Borkakoti, N.]]
[[Category: Lindberg, J.]]
[[Category: Nystrom, S.]]
[[Category: Alternative splicing]]
[[Category: Aspartyl protease]]
[[Category: Bace]]
[[Category: Beta secretase-1]]
[[Category: Disulfide bond]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Inhibitor]]
[[Category: Membrane]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  3 15:55:17 2010''

Revision as of 13:55, 3 March 2010

File:3ixj.jpg

Template:STRUCTURE 3ixj

Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor

Template:ABSTRACT PUBMED 20128595

About this Structure

3IXJ is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bjorklund C, Oscarson S, Benkestock K, Borkakoti N, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist A, Samuelsson B. Design and synthesis of potent and selective BACE-1 inhibitors. J Med Chem. 2010 Feb 25;53(4):1458-64. PMID:20128595 doi:10.1021/jm901168f

Page seeded by OCA on Wed Mar 3 15:55:17 2010

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