Sandbox 179: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 5: Line 5:
Protein Function
Protein Function


Pepsin is one of three proteolytic, or protein degrading enzymes in the digestive system. It resides in the alimentary canal and is produced by mucosal cells (1).  Pepsin degrades peptides, and is optimally active at low pHs (1). Pepsin is an aspartic proteinase, more specifically a eukaryotic aspartic protease enzyme (3).  Aspartic proteinases are widespread in nature, and pepsin in particular has been known to be medically important (2).   
Pepsin is one of three proteolytic, or protein degrading enzymes in the digestive system. It resides in the alimentary canal and is produced by mucosal cells <ref>.  Pepsin degrades peptides, and is optimally active at low pHs <ref>. Pepsin is an aspartic proteinase, more specifically a eukaryotic aspartic protease enzyme (3).  Aspartic proteinases are widespread in nature, and pepsin in particular has been known to be medically important (2).   
----
----
Overall Structure
Overall Structure
----
----
=References=
<references/>

Revision as of 04:07, 24 March 2010

Pepsin


Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. Andrea Gorrell.
Drag the structure with the mouse to rotate
5pep, resolution 2.34Å (default scene)
Activity: Pepsin A, with EC number 3.4.23.1
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml


Protein Function

Pepsin is one of three proteolytic, or protein degrading enzymes in the digestive system. It resides in the alimentary canal and is produced by mucosal cells <ref>. Pepsin degrades peptides, and is optimally active at low pHs <ref>. Pepsin is an aspartic proteinase, more specifically a eukaryotic aspartic protease enzyme (3). Aspartic proteinases are widespread in nature, and pepsin in particular has been known to be medically important (2).


Overall Structure


References