Sandbox 179: Difference between revisions

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Protein Function
Protein Function


Pepsin is one of three proteolytic, or protein degrading enzymes in the digestive system. It resides in the alimentary canal and is produced by mucosal cells <ref>. Pepsin degrades peptides, and is optimally active at low pHs <ref>. Pepsin is an aspartic proteinase, more specifically a eukaryotic aspartic protease enzyme (3).  Aspartic proteinases are widespread in nature, and pepsin in particular has been known to be medically important (2).   
Pepsin is one of three proteolytic, or protein degrading enzymes in the digestive system. It resides in the alimentary canal and is produced by mucosal cells. Pepsin degrades peptides, and is optimally active at low pHs <ref> X-ray analyses of aspartic proteinases. II. Three-dimensional structure of the hexagonal crystal form of porcine pepsin at 2.3 A resolution. 1990;214:199-222</ref>. Pepsin is an aspartic proteinase, more specifically a eukaryotic aspartic protease enzyme (3).  Aspartic proteinases are widespread in nature, and pepsin in particular has been known to be medically important (2).   
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Overall Structure
Overall Structure