Sandbox 174: Difference between revisions
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=Functions= | =Functions= | ||
Elapidae neurotoxins bind specifically and tightly in a non-covalent manner to the nicotinic acetylcholine receptors in cholinergic synapses of their victims. This prevents normal neurotransmitter-induced channel opening, which in turn blocks postsynaptic membrane depolarization<ref>Love. A.R (FINISH)</ref>. | Elapidae neurotoxins bind specifically and tightly in a non-covalent manner to the nicotinic acetylcholine receptors in cholinergic synapses of their victims. This prevents normal neurotransmitter-induced channel opening, which in turn blocks postsynaptic membrane depolarization<ref name="main">Love. A.R (FINISH)</ref>. | ||
==α7 nicotinic acetylcholine receptor binding== | ==α7 nicotinic acetylcholine receptor binding== | ||
Reponse to sensory stimuli and seizure genesis has been linked to nicotinic mechanisms<ref name="main">a-Bungarotoxin Binding to Hippocampal Interneurons: | Reponse to sensory stimuli and seizure genesis has been linked to nicotinic mechanisms<ref name="main">a-Bungarotoxin Binding to Hippocampal Interneurons: | ||
