Sandbox 156: Difference between revisions
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==Structure== | ==Structure== | ||
The general structure of CAT III is dominated by a six stranded antiparallel <scene name='Sandbox_156/Scene_4/4'>β-sheet</scene> and 5 <scene name='Sandbox_156/Scene_4/3'>α-helices</scene> stacked against the ends and face of the protein, forming a structure known as an "open-faced sandwhich". <ref>PMID: 3288984</ref> | |||
{{STRUCTURE_4CLA | PDB=4CLA | Scene=Sandbox_156/Scene_1/1}} | {{STRUCTURE_4CLA | PDB=4CLA | Scene=Sandbox_156/Scene_1/1}} | ||
<applet load='4CLA' size='300' frame='true' align='right' caption='' /> | <applet load='4CLA' size='300' frame='true' align='right' caption='' /> | ||
<scene name='Sandbox_156/Scene_1/1'>binding site?</scene> | <scene name='Sandbox_156/Scene_1/1'>binding site?</scene> | ||
<scene name='Sandbox_156/Scene_two/1'>His-195</scene> | <scene name='Sandbox_156/Scene_two/1'>His-195</scene> | ||
<scene name='Sandbox_156/Scene_4/2'>bridging hydrogen bond</scene> | |||
<scene name='Sandbox_156/Scene_3/1'>active site</scene> | <scene name='Sandbox_156/Scene_3/1'>active site</scene> | ||
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<scene name='Sandbox_156/Scene_4/1'>Tyr-25</scene> | <scene name='Sandbox_156/Scene_4/1'>Tyr-25</scene> | ||
<scene name='Sandbox_156/Scene_5/2'>Ser-148</scene> | <scene name='Sandbox_156/Scene_5/2'>Ser-148</scene> | ||
