Collagen Structure & Function: Difference between revisions
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=='''Collagen'''== | =='''Collagen'''== | ||
<applet load='1cag' size='400' frame='true' align='right' caption='Collagen at 1.9A resolution' /> | |||
==Introduction== | ==Introduction== | ||
[[Image:collagen.png|thumb]] | |||
Collagen is a member of a family of naturally occurring proteins. It is one of the most plentiful proteins present in mammals and is responsible for performing a variety of biological functions. It is present in large quantities in connective tissue and provides tendons and ligaments with tensile strength and skin with elasticity.It often works in conjuction with other important proteins such as keratin and elastin. | Collagen is a member of a family of naturally occurring proteins. It is one of the most plentiful proteins present in mammals and is responsible for performing a variety of biological functions. It is present in large quantities in connective tissue and provides tendons and ligaments with tensile strength and skin with elasticity.It often works in conjuction with other important proteins such as keratin and elastin. | ||
==Molecular Structure== | ==Molecular Structure== | ||
[[Image:collagen1.png|thumb]] | |||
The shape and structural properties of a native collagen molecule are established by its triple-helical domain(s). In classical collagen molecules a single triple-helical domain is observed to compose close to 95% of the molecule <ref>PMID: 19853297</ref>. However there are also other types of collagens that have been shown to comprise of multiple triple-helical domains which only account for a fraction of the molecules mass. | The shape and structural properties of a native collagen molecule are established by its triple-helical domain(s). In classical collagen molecules a single triple-helical domain is observed to compose close to 95% of the molecule <ref>PMID: 19853297</ref>. However there are also other types of collagens that have been shown to comprise of multiple triple-helical domains which only account for a fraction of the molecules mass. | ||
