Pilin: Difference between revisions

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PilS causes typhoid by entering the enterocytes and specialized M cells of the small intestine. After entry, it is transferred to the intestinal submucosa and is taken up by host macrophages. The overall mechanism of the entry into the enterocytes is complicated and involves intercellular adhesins and intracellular signaling which change the host cell's vacuolar and cytoskeletal organization. <ref name=journal1>PMID:19626704</ref>
PilS causes typhoid by entering the enterocytes and specialized M cells of the small intestine. After entry, it is transferred to the intestinal submucosa and is taken up by host macrophages. The overall mechanism of the entry into the enterocytes is complicated and involves intercellular adhesins and intracellular signaling which change the host cell's vacuolar and cytoskeletal organization. <ref name=journal1>PMID:19626704</ref>