1yy9: Difference between revisions

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{{ABSTRACT_PUBMED_15837620}}
{{ABSTRACT_PUBMED_15837620}}
==Disease==
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]]


==About this Structure==
==About this Structure==
1YY9 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus/homo_sapiens Mus musculus/homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YY9 OCA].  
1YY9 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus,_homo_sapiens Mus musculus, homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YY9 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15837620</ref><references group="xtra"/>
<ref group="xtra">PMID:15837620</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus/homo sapiens]]
[[Category: Mus musculus, homo sapiens]]
[[Category: Transferase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Ferguson, K M.]]
[[Category: Ferguson, K M.]]
[[Category: Jeffrey, P D.]]
[[Category: Jeffrey, P D.]]
Line 42: Line 39:
[[Category: Fab fragment]]
[[Category: Fab fragment]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Immune system-transferase complex]]
[[Category: Tyrosine kinase]]
[[Category: Tyrosine kinase]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 12:57:37 2010''

Revision as of 09:57, 31 March 2010

File:1yy9.png

Template:STRUCTURE 1yy9

Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225

Template:ABSTRACT PUBMED 15837620

About this Structure

1YY9 is a 3 chains structure with sequences from Homo sapiens and Mus musculus, homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell. 2005 Apr;7(4):301-11. PMID:15837620 doi:10.1016/j.ccr.2005.03.003

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