Sandbox 160: Difference between revisions
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== '''Glyceraldehyde 3-Phosphate Dehydrogenase'''== | |||
== Introduction == | == Introduction == | ||
{{STRUCTURE_1vc2| PDB=1vc2 | Scene =Sandbox_160/Newscene/1'>active site }} | {{STRUCTURE_1vc2| PDB=1vc2 | Scene =Sandbox_160/Newscene/1'>active site }} | ||
Glyceraldehyde 3-Phosphate dehydrogenase (GAPDH) is an Oxidoreductase enzyme and is involved in many important biochemical reactions. This protein is responsible for catalyzing the conversion of glyceraldeyde 3-Phosphate into 1,3-Biphosphoglycerate in a two step coupled mechanism. This conversion occurs during step 6 or the beginning of the "payoff phase" of glycolysis (the second half of the entire process) in which ATP and NADH is produced. A total of 2 NADH and 4 ATP are produced during this phase for a net gain of 2 NADH and 2 ATP for the entire glycolysis pathway per glucose. | Glyceraldehyde 3-Phosphate dehydrogenase (GAPDH) is an Oxidoreductase enzyme and is involved in many important biochemical reactions. It is involved in glycolysis, gluconeogenesis and in the case of photosynthetic organism, the carbon reduction cycle <ref name="reference 2"/>. This protein is responsible for catalyzing the conversion of glyceraldeyde 3-Phosphate into 1,3-Biphosphoglycerate in a two step coupled mechanism. This conversion occurs during step 6 or the beginning of the "payoff phase" of glycolysis (the second half of the entire process) in which ATP and NADH is produced. A total of 2 NADH and 4 ATP are produced during this phase for a net gain of 2 NADH and 2 ATP for the entire glycolysis pathway per glucose. | ||
== Structure & Function == | == Structure & Function == | ||
