Sandbox 171: Difference between revisions
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===Structure=== | ===Structure=== | ||
Myosin has a molecular size of approximately 520 kilodaltons, with two 220 kD heavy chains and two pairs of light chains which vary in size. <ref name="Rayment">PMID: 8316857</ref> The molecule is asymmetric, having a long tail and two globular heads. <ref name="Rayment" /> | Myosin has a molecular size of approximately 520 kilodaltons, with two 220 kD heavy chains and two pairs of light chains which vary in size. <ref name="Rayment">PMID: 8316857</ref> The molecule is asymmetric, having a long tail and two globular heads. <ref name="Rayment" /> Each heavy chains composes the bulk of one of the globular heads. <ref name="Rayment" /> Subfragment-1(S1) also termed the myosin head consists of ATP, actin, and two light chain binding sites.<ref name="Rayment" /> Each globular head has a heavy chain and two light chains for a combined molecular size of about 130 kD. <ref name="Rayment" /> | ||
[[Image:Myosin_head.gif|thumb|alt=Alt text|Myosin head]] | [[Image:Myosin_head.gif|thumb|alt=Alt text|Myosin head]] | ||
[[Image:Myosin_chains.gif|thumb|alt=Alt text|Myosin filament]] | [[Image:Myosin_chains.gif|thumb|alt=Alt text|Myosin filament]] | ||
