Sandbox 154: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Melissa Chow (talk | contribs) |
Melissa Chow (talk | contribs) |
||
| Line 62: | Line 62: | ||
The dynamic functions of f-actin are heavily involved with [http://en.wikipedia.org/wiki/Cell_migration/ cell migration]<ref name="stricker">PMID:19913792</ref>. | The dynamic functions of f-actin are heavily involved with [http://en.wikipedia.org/wiki/Cell_migration/ cell migration]<ref name="stricker">PMID:19913792</ref>. | ||
==== Cytoskeleton ==== | ==== [http://en.wikipedia.org/wiki/Cytoskeleton#Actin_filaments_.2F_Microfilaments Cytoskeleton] ==== | ||
F-actin is the most abundant component of the cytoskeleton of eukaryotes. It provides large amounts of tensile strength, considering its thin size. In cases where the flexibility is not desirable as a strucutral component, crosslinkages can be formed between F-actin polymers to give greater stiffness and support<ref name="Mitchinson"/>. | F-actin is the most abundant component of the cytoskeleton of eukaryotes. It provides large amounts of tensile strength, considering its thin size. In cases where the flexibility is not desirable as a strucutral component, crosslinkages can be formed between F-actin polymers to give greater stiffness and support<ref name="Mitchinson"/>. | ||
Elongation of F-actin branches leads to the phenomenon of pushing of the plasma membrane forward in lamellopodial and filopodial extension<ref name="Chen"/>. This process relies on the dynamic equlibrium state in which G- and F-actin exist, as it is the continual polymerization of actin units on the leading edge that propels the membrane extension. Without the enzymatic ATPase function of F-actin, this process would not be possible. | Elongation of F-actin branches leads to the phenomenon of pushing of the plasma membrane forward in lamellopodial and filopodial extension<ref name="Chen"/>. This process relies on the dynamic equlibrium state in which G- and F-actin exist, as it is the continual polymerization of actin units on the leading edge that propels the membrane extension. Without the enzymatic ATPase function of F-actin, this process would not be possible. | ||
==== Actin-Myosin ==== | ==== Actin-Myosin ==== | ||
