Crystal contacts: Difference between revisions
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In contrast, contacts between chains that occur in the native functional state of the molecule are called ''specific oligomeric contacts''. The resulting functional quaternary structure is called the [[Biological unit|biological unit or biological assembly]]. Specific oligomeric contacts occur through interfaces that have co-evolved to fit together and bind under the proper circumstances. Some molecules have multiple quaternary forms. For example, protein phosphorylation often controls the affinities of partner chains for each other. | In contrast, contacts between chains that occur in the native functional state of the molecule are called ''specific oligomeric contacts''. The resulting functional quaternary structure is called the [[Biological unit|biological unit or biological assembly]]. Specific oligomeric contacts occur through interfaces that have co-evolved to fit together and bind under the proper circumstances. Some molecules have multiple quaternary forms. For example, protein phosphorylation often controls the affinities of partner chains for each other. | ||
Crystal contacts tend to be smaller and to involve more hydrophilic surfaces, in contrast to specific oligomeric contacts which are larger and may bury some hydrophobic surface<ref>PMID: 9261866</ref>. | Crystal contacts tend to be smaller and to involve more hydrophilic surfaces, in contrast to specific oligomeric contacts which are larger and may bury some hydrophobic surface<ref>PMID: 9406542</ref> <ref>PMID: 9261866</ref>. | ||
==References== | ==References== | ||
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