Crystal contacts: Difference between revisions

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In contrast, contacts between chains that occur in the native functional state of the molecule are called ''specific oligomeric contacts''. The resulting functional quaternary structure is called the [[Biological unit|biological unit or biological assembly]]. Specific oligomeric contacts occur through interfaces that have co-evolved to fit together and bind under the proper circumstances. Some molecules have multiple quaternary forms. For example, protein phosphorylation often controls the affinities of partner chains for each other.
In contrast, contacts between chains that occur in the native functional state of the molecule are called ''specific oligomeric contacts''. The resulting functional quaternary structure is called the [[Biological unit|biological unit or biological assembly]]. Specific oligomeric contacts occur through interfaces that have co-evolved to fit together and bind under the proper circumstances. Some molecules have multiple quaternary forms. For example, protein phosphorylation often controls the affinities of partner chains for each other.


Crystal contacts tend to be smaller and to involve more hydrophilic surfaces, in contrast to specific oligomeric contacts which are larger and may bury some hydrophobic surface<ref>PMID: 9261866</ref>.
Crystal contacts tend to be smaller and to involve more hydrophilic surfaces, in contrast to specific oligomeric contacts which are larger and may bury some hydrophobic surface<ref>PMID: 9406542</ref> <ref>PMID: 9261866</ref>.


==References==
==References==
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