Reverse transcriptase: Difference between revisions

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This seems to be the most general idea of the mechanism of action of Reverse Transcriptase, however the process remains unclear and new approaches are being reported. [http://www.nature.com/nature/journal/v453/n7192/full/nature06941.html]
This seems to be the most general idea of the mechanism of action of Reverse Transcriptase, however the process remains unclear and new approaches are being reported. [http://www.nature.com/nature/journal/v453/n7192/full/nature06941.html]


One of the principal issues about this protein comparative with the usual DNA polymerase (besides to the similarity with the Klenow fragment), is the lack of a correction mechanism (usually made by DNA PolIII in the DNA Pol) that increase the quota of errors, producing more mutations and by this way giving more facultative and resistance abilities to the virus.
One of the principal issues about this protein comparative with the usual DNA polymerase (besides to the similarity with the Klenow fragment), is the lack of a correction mechanism (usually made by DNA PolIII in the [[User:Karl E. Zahn/RB69 DNA polymerase (GP43)|DNA Polymerase]]) that increase the quota of errors, producing more mutations and by this way giving more facultative and resistance abilities to the virus.


==See Also==
==See Also==