3ho5: Difference between revisions
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===Crystal structure of Hedgehog-interacting protein (HHIP) and Sonic hedgehog (SHH) complex=== | ===Crystal structure of Hedgehog-interacting protein (HHIP) and Sonic hedgehog (SHH) complex=== | ||
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==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
3HO5 is a 3 chains structure | 3HO5 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HO5 OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:19561609</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bosanac, I.]] | [[Category: Bosanac, I.]] | ||
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[[Category: Zinc cation]] | [[Category: Zinc cation]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:48:23 2010'' | ||
Revision as of 07:48, 28 April 2010
Crystal structure of Hedgehog-interacting protein (HHIP) and Sonic hedgehog (SHH) complex
Template:ABSTRACT PUBMED 19561609
Disease
Known disease associated with this structure: Coloboma, ocular OMIM:[600725], Holoprosencephaly-3 OMIM:[600725], Microphthalmia, isolated, with coloboma 5 OMIM:[600725], Solitary median maxillary central incisor OMIM:[600725]
About this Structure
3HO5 is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bosanac I, Maun HR, Scales SJ, Wen X, Lingel A, Bazan JF, de Sauvage FJ, Hymowitz SG, Lazarus RA. The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling. Nat Struct Mol Biol. 2009 Jul;16(7):691-7. Epub 2009 Jun 28. PMID:19561609 doi:10.1038/nsmb.1632
Page seeded by OCA on Wed Apr 28 10:48:23 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Bosanac, I.
- Hymowitz, S G.
- Alternative splicing
- Autocatalytic cleavage
- Calcium cation
- Cell membrane
- Cytoplasm
- Developmental protein
- Disease mutation
- Disulfide bond
- Egf domain
- Egf-like domain
- Glycoprotein
- Holoprosencephaly
- Hydrolase
- Lipoprotein
- Membrane
- Microphthalmia
- Palmitate
- Polymorphism
- Protease
- Receptor ectodomain
- Secreted
- Signaling protein
- Six-bladed-propeller domain
- Zinc cation
