3hnb: Difference between revisions
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===Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor=== | ===Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor=== | ||
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{{ABSTRACT_PUBMED_20089867}} | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
3HNB is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HNB OCA]. | 3HNB is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HNB OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:20089867</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Liu, Z.]] | [[Category: Liu, Z.]] | ||
[[Category: Yuan, C.]] | [[Category: Yuan, C.]] | ||
[[Category: Blood clotting]] | |||
[[Category: Small molecule inhibitor/blood clotting]] | [[Category: Small molecule inhibitor/blood clotting]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:59:07 2010'' | ||
Revision as of 07:59, 28 April 2010
Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
Template:ABSTRACT PUBMED 20089867
Disease
Known disease associated with this structure: Hemophilia A OMIM:[306700]
About this Structure
3HNB is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Liu Z, Lin L, Yuan C, Nicolaes GA, Chen L, Meehan EJ, Furie B, Furie B, Huang M. Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding. J Biol Chem. 2010 Mar 19;285(12):8824-9. Epub 2010 Jan 20. PMID:20089867 doi:10.1074/jbc.M109.080168
Page seeded by OCA on Wed Apr 28 10:59:07 2010
