Factor VIIa: Difference between revisions

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===Kinetics of action===
===Kinetics of action===
In general serine proteases have a three-step kinetic mechanim: 1) formation of an enzyme-substrate (E-S) complex, 2) acylation of the active site serine, and 3) hydrolysis of the acylenzyme intermediate.   
In general serine proteases have a three-step kinetic mechanim: 1) formation of an enzyme-substrate (E-S) complex, 2) acylation of the active site serine, and 3) hydrolysis of the acylenzyme intermediate.   
[[Image:kin mech.jpg|center]]
 


===Catalytic domain===
===Catalytic domain===
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