Disulfide Connectivity of Velaglucerase: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
Joel L. Sussman (talk | contribs)
ConfirmAccount, Editor, Mutation, Print3D, Tester, Bureaucrats, journal
11,640 edits
No edit summary
Joel L. Sussman (talk | contribs)
ConfirmAccount, Editor, Mutation, Print3D, Tester, Bureaucrats, journal
11,640 edits
No edit summary
Line 4: Line 4:
{{Clear}}
{{Clear}}
<applet load='1ogs' size='[450,338]' frame='true' align='right'
<applet load='1ogs' size='[450,338]' frame='true' align='right'
caption='Human beta-glucocerebrosidase (1ogs)<ref>FDvir H, Harel M, McCarthy AA, Toker L, Silman I, Futerman AH, Sussman JL, EMBO Rep. 2003 Jul;4(7):704-9.  PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14764885 12792654]</ref>' scene='User:Adriana_Kita/Sandbox_1/Gcase_whole/5'/>
caption='Human beta-glucocerebrosidase (1ogs)' scene='User:Adriana_Kita/Sandbox_1/Gcase_whole/5'/>


Human beta-glucocerebrosidase, also known as glucoceremidase, GCase, and velaglucerase, is an enzyme that is commonly found to be deficient in patients with Gaucher's disease.  
Human beta-glucocerebrosidase, PDB ID 1ogs <ref>Ferreira, K.N., Iverson, T.M., Maghlaoui, K., Barber, J., Iwata, S.  "Architecture of the photosynthetic oxygen-evolving center."  Science, March 19, 2004, 303 (5665), 1831-8.  PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14764885 14764885]</ref>.also known as glucoceremidase, GCase, and velaglucerase, is an enzyme that is commonly found to be deficient in patients with Gaucher's disease.  


Currently, there are two drugs on the market to treat this disease. One being Genzyme's Cerezyme and the other SHIRE's VPRIV.  
Currently, there are two drugs on the market to treat this disease. One being Genzyme's Cerezyme and the other SHIRE's VPRIV.  
Retrieved from "https://proteopedia.org/Disulfide_Connectivity_of_Velaglucerase"