Disulfide Connectivity of Velaglucerase: Difference between revisions

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Joel L. Sussman (talk | contribs)
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caption='Human beta-glucocerebrosidase (1ogs)' scene='User:Adriana_Kita/Sandbox_1/Gcase_whole/5'/>
caption='Human beta-glucocerebrosidase (1ogs)' scene='User:Adriana_Kita/Sandbox_1/Gcase_whole/5'/>


Human beta-glucocerebrosidase, PDB ID 1ogs <ref>Ferreira, K.N., Iverson, T.M., Maghlaoui, K., Barber, J., Iwata, S.  "Architecture of the photosynthetic oxygen-evolving center."  Science, March 19, 2004, 303 (5665), 1831-8.  PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14764885 14764885]</ref>, also known as glucoceremidase, GCase, and velaglucerase, is an enzyme that is commonly found to be deficient in patients with Gaucher's disease.  
Human beta-glucocerebrosidase, PDB ID 1ogs <ref>PMID:14764885</ref>, also known as glucoceremidase, GCase, and velaglucerase, is an enzyme that is commonly found to be deficient in patients with Gaucher's disease.  


Currently, there are two drugs on the market to treat this disease. One being Genzyme's Cerezyme and the other SHIRE's VPRIV.  
Currently, there are two drugs on the market to treat this disease. One being Genzyme's Cerezyme and the other SHIRE's VPRIV.  
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